The Clinical Research Unit of Nanoro (IRSS-CRUN) was created in 2008 to provide a much-needed Good Clinical Practices (GCP) compliant trial platform for training and research activities. The CRUN’s mission is to provide evidence-based information for the health care of populations living in tropical countries. The team’s scientific interest at the creation in 2008 was mainly malaria research and the team implemented several studies in this topic including the GSK RTS,S phase 3 malaria vaccine candidate trial. However, with the epidemiological transition leading to a decline of malaria global incidence in the last decade, other infectious diseases are becoming of more important public health concern, especially in sub-Saharan Africa. In this context, since the last five years the CRUN has gradually diversified its research portfolio to consider other diseases besides malaria.
We set-up in 2009 a Health and Demographic Surveillance System (HDSS) of about 66,000 people. Since then, a dynamic approach was used engaging local community throughout the process. With a multidisciplinary team, we completed more than 40 research (3 trials on malaria vaccine) projects and published 140 articles in peer review journals in the last ten years.

For more information visit the CRUN website or contact info [at] crun [dot] bf (via email)